Job quality indexes are constructed on the basis of such aspects of working conditions as earnings, prospects, working time, and intrinsic job quality. Occupations where job quality is consistently low are labelled ‘occupations with multiple disadvantages’. This report uses data from the fifth European Working Conditions Survey to identify such occupations. It finds that workers in mid-skilled manual and lowskilled occupations do quite poorly when it comes to earnings, prospects and intrinsic job quality, and they report relatively low levels of both physical and mental well-being. However, their working time quality is generally good. In contrast, workers in high-skilled occupations do relatively well on almost all job quality indicators, except working time.